M272: STEM CELL BIOLOGY AND REGENERATIVE MEDICINE

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READING LIST (revised 4/20/07)

Week 1:
Gadue, P., Huber, T.L., Nostro, M.C., Kattman, S., Keller, G.M. 2005 Germ layer induction from embryonic stem cells. Exp. Hematol. 33:955-964.

Week 2:
Seydoux, G., Braun, R.E. 2006. Pathway to totipotency: lessons from germ cells. Cell 127:891-904.

Trounson, A. 20006. The production and directed differentiation of human embryonic stem cells. Endocrine Reviews 27:208-219.

Week 3:
Pyle lecture:
Spagnoli, F.M., Hemmati-Brivaniou, A. 2006. Guiding embryonic stem cells towards differentiation: lessons from molecular embryology. Curr. Opin. Genetics and Develop. 16:469-475.

Avery, S., Inniss, K., Moore, H. 2006. The reguation of self-renewal in human embryonic stem cells. Stem Cells and Develop. 15:729-740.

Wang, J., Rao, S., Chu, J., Shen, X., Levasseru, D.N. Theunissen, T.W., Orkin, S.H. 2006. A protein interaction network for pluripotency of embryonic stem cells. Nature 444:364-368.

Plath lecture:
Hochedlinger, K. Jaenisch, R. 2006. Nuclear reprogramming and pluripotency. Nature 441:1061-1067.

Meshorer, E Misteli, T. Chromatin in pluripotent embryonic stem cells and differentiation. Nature Rev. Mol. Cell Biol. 7:540-546.

Buszcak, M. Spradling, A.C. 2006. Searching chromatin for stem cell identity. Cell 125:233-236.

Week 4: (updated 4/5/07)
Wu lecture:
Reya, T., Morrison, S.J., Clarke, M.F., Weissman, I.L. Stem cells, cancer, and cancer stem cells. Nature 414:105-111.

Week 5:
Parhami lecture:
Vaananen, H.K. 2005. Mesenchymal stem cells. Annal. Med. 37:469-479.

Baksh, D., Song, L, Tuan, R.S. 2004. Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J. Cell. Mol. Med. 8:301-316.

MacClellan lecture:
Rubart, M., Field, L.J. 2006. Cardiac regeneration: repopulating the heart. Annu. Rev. Physiol. 68:29-49.

Garry, D.J., Olsen, E.N. 2006. A common progenitor at the heart of development. Cell 127:1101-1104.

Week 6: (updated 4/20/07)
Kornblum lecture:
Lindval, O., Kokaia, Z., Stem Cells for the Treatment of Neurological Disorders, Nature, v441, June 29, 2006: 1094-1096.

Kornblum, H., Introduction to Neural Stem Cells, Stroke, 2007;38;810-816.

Week 7:
Iruela-Arispe lecture:
Jaffredo, T., Jnottingham, W., Liddiard, K., Bollerot, K., Pouget, C., de Bruijn, M.2005. From hemangioblast to hematopoietic stem cell: an endothelial connection? Exp. Hematol. 33:1029-1040.

Barber, C.L., Iruela-Arispe, M.L. 2006. The ever-elusive endothelial progenitor cell: identities, functions, and clinical implications. Ped. Res. 59:26R32R.

Dorshkind lecture:
Bryder, D., Rossi, D.J., Weissman, I.L. 2006. Hematopietic stem cells: The paradigmatic tissue-specific stem cell. Am. J. Pathol. 338-346.

Dorshkind, K., Montecino-Rodriguez, E. 2007. Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential. Nat. Rev. Immunol. 7:213-219.

Scaden, D.T. 2006. The stem-cell niche as an entity of action. Nature 441:1075-1079.

Week 8:
Dorshkind lecture 1:
Shizuru, J.A., Negrin, R.S., Weissman, I.L. 2005. Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system.  Annu. Rev. Med. 56:509-538.

Nienhuis, A.W., Dunbar, C.E., Sorrentino, B.P. 2006. Genotoxicity of retroviral integration in hematopoietic cells. Mol. Therapy 13:1031-1049.

Dorshkind lecture 2:
Oakley, E.J., Van Zant, G. 2007. Unraveling the complex regulation of stem cells: implications for aging and cancer. Leukemia  21:6120621.

Kim, W.Y., Sharpless, N.E. 2006. The regulation of Ink4/ARF in cancer and aging. Cell 127:265-275.

Week 9:
Not yet assigned

Week 10:
Not yet assigned